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Terms of Service

Last Updated: November 2, 2022

Welcome, and thank you for your interest in Sinaptica Therapeutics, Inc. (“Sinaptica,” “we,” or “us”) and our website at sinapticatx.com, including subdomains of that website (collectively, the “Site”). These Terms of Use are a legally binding contract between you and Sinaptica regarding your use of the Site.

PLEASE READ THE FOLLOWING TERMS CAREFULLY.

BY ACCESSING OR USING THE SITE, YOU AGREE THAT YOU HAVE READ AND UNDERSTOOD, AND, AS A CONDITION TO YOUR USE OF THE SITE, YOU AGREE TO BE BOUND BY, THE FOLLOWING TERMS AND CONDITIONS, INCLUDING THE PRIVACY POLICY (DEFINED BELOW) (TOGETHER, THESE “TERMS”). If you are not eligible, or do not agree to the Terms, then you do not have our permission to use the SITE. YOUR USE OF THE SITE, AND SINAPTICA’S PROVISION OF THE SITE TO YOU, CONSTITUTES AN AGREEMENT BY SINAPTICA AND BY YOU TO BE BOUND BY THESE TERMS.

1. Overview. The Site provides information about Sinaptica and our clinical research about treatments for Alzheimer’s Disease. Sinaptica does not currently have any FDA or other approved product or treatment for Alzheimer’s Disease, and does not provide any medical advice on its Site. 

2. Eligibility. You must be at least 18 years old to use the Site. By agreeing to these Terms, you represent and warrant to us that: (a) you are at least 18 years old; (b) you have not previously been suspended or removed from the Site or any other service provided by Sinaptica; and (c) your use of the Site is in compliance with any and all applicable laws and regulations. 

3. Licenses

3.1 Limited License. Subject to your complete and ongoing compliance with these Terms, Sinaptica grants you, solely for your personal, use, a limited, non-exclusive, non-transferable, non-sublicensable, revocable license to access and use the Site. 

3.2 License Restrictions. Except and solely to the extent such a restriction is impermissible under applicable law, you may not: (a) reproduce, distribute, publicly display, or publicly perform the Site; (b) make modifications to the Site; or (c) interfere with or circumvent any feature of the Site, including any security or access control mechanism. If you are prohibited under applicable law from using the Site, you may not use it.

3.3 Information You Submit. Do not submit any information or other materials that you consider confidential or proprietary through the Site. If you choose to provide input and suggestions regarding problems with or proposed modifications or improvements to the Site (“Feedback”), then you do so on a non-confidential basis (regardless of any designation or indication to the contrary in the submitted information or any accompanying correspondence) and you hereby grant Sinaptica an unrestricted, perpetual, irrevocable, non-exclusive, fully-paid, royalty-free transferable, sublicensable right to exploit the Feedback in any manner and for any purpose, including to improve the Site and create other products and services.

4. Ownership; Proprietary Rights. The Site is owned and operated by Sinaptica. The visual interfaces, graphics, design, compilation, information, data, computer code (including source code or object code), products, software, services, and all other elements of the Site (“Materials”) provided by Sinaptica are protected by intellectual property and other laws. All Materials included in the Site are the property of Sinaptica or its third-party licensors. Except as expressly authorized by Sinaptica, you may not make use of the Materials. Sinaptica reserves all rights to the Materials not granted expressly in these Terms.

5. Linked Websites. The Site may contain links to third party websites. Linked websites are not under Sinaptica’s control, and Sinaptica is not responsible for their content. 

6. Prohibited Conduct. BY USING THE SITE YOU AGREE NOT TO: 

a. use the Site for any illegal purpose or in violation of any local, state, national, or international law;

b. violate, or encourage others to violate, any right of a third party, including by infringing or misappropriating any third-party intellectual property right;

c. interfere with security-related features of the Site, including by: (i) disabling or circumventing features that prevent or limit use or copying of any content; or (ii) reverse engineering or otherwise attempting to discover the source code of any portion of the Site except to the extent that the activity is expressly permitted by applicable law;

d. interfere with the operation of the Site or any user’s enjoyment of the Site, including by uploading or otherwise disseminating any virus, adware, spyware, worm, or other malicious code or interfering with or disrupting any network, equipment, or server connected to or used to provide the Site;

e. perform any fraudulent activity including impersonating any person or entity, or claiming a false affiliation;

f. sell or otherwise transfer the access granted under these Terms or any Materials or any right or ability to view, access, or use any Materials; or

g. attempt to do any of the acts described in this Section 7 or assist or permit any person in engaging in any of the acts described in this Section 7.

7. Modification of these Terms. We reserve the right to change these Terms on a going-forward basis at any time. Please check these Terms periodically for changes. Except as expressly permitted in this Section 8, these Terms may be amended only by a written agreement signed by authorized representatives of the parties to these Terms. Disputes arising under these Terms will be resolved in accordance with the version of these Terms that was in effect at the time the dispute arose. 

8. Modification of the Site. Sinaptica reserves the right to modify or discontinue the Site at any time (including by limiting or discontinuing certain features of the Site), temporarily or permanently, without notice to you. Sinaptica will have no liability for any change to the Site or any suspension or termination of your access to or use of the Site. 

9. Term. These Terms are effective beginning when you accept the Terms or first access, or use the Site, and ending when terminated as described in this Section 10. If you violate any provision of these Terms, your authorization to access the Site and these Terms automatically terminate. In addition, Sinaptica may, at its sole discretion, terminate these Terms, or suspend or terminate your access to the Site, at any time for any reason or no reason, with or without notice. Upon termination of these Terms: (a) your license rights will terminate and you must immediately cease all use of the Site; (b) you will no longer be authorized to access the Site; and (c) Sections 4.3, 5, 10, 11, 12, 13, and 14 will survive. 

10. Indemnity. To the fullest extent permitted by law, you are responsible for your use of the Site, and you will defend and indemnify Sinaptica and its officers, directors, employees, consultants, affiliates, subsidiaries and agents (together, the “Sinaptica Entities”) from and against every claim brought by a third party, and any related liability, damage, loss, and expense, including reasonable attorneys’ fees and costs, arising out of or connected with: (a) your unauthorized use of, or misuse of, the Site; (b) your violation of any portion of these Terms, any representation, warranty, or agreement referenced in these Terms, or any applicable law or regulation; (c) your violation of any third party right, including any intellectual property right or publicity, confidentiality, other property, or privacy right; or (d) any dispute or issue between you and any third party. We reserve the right, at our own expense, to assume the exclusive defense and control of any matter otherwise subject to indemnification by you (without limiting your indemnification obligations with respect to that matter), and in that case, you agree to cooperate with our defense of those claims.

11. Disclaimers; No Warranties

11.1 THE SITE AND ALL MATERIALS AND CONTENT AVAILABLE THROUGH THE SITE ARE PROVIDED “AS IS” AND ON AN “AS AVAILABLE” BASIS. SINAPTICA DISCLAIMS ALL WARRANTIES OF ANY KIND, WHETHER EXPRESS OR IMPLIED, RELATING TO THE SITE AND ALL MATERIALS AND CONTENT AVAILABLE THROUGH THE SITE, INCLUDING: (a) ANY IMPLIED WARRANTY OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE, TITLE, QUIET ENJOYMENT, OR NON-INFRINGEMENT; AND (b) ANY WARRANTY ARISING OUT OF COURSE OF DEALING, USAGE, OR TRADE. SINAPTICA DOES NOT WARRANT THAT THE SITE OR ANY PORTION OF THE SITE, OR ANY MATERIALS OR CONTENT OFFERED THROUGH THE SITE, WILL BE UNINTERRUPTED, SECURE, OR FREE OF ERRORS, VIRUSES, OR OTHER HARMFUL COMPONENTS, AND SINAPTICA DOES NOT WARRANT THAT ANY OF THOSE ISSUES WILL BE CORRECTED.

11.2 NO ADVICE OR INFORMATION, WHETHER ORAL OR WRITTEN, OBTAINED BY YOU FROM THE SITE OR SINAPTICA ENTITIES OR ANY MATERIALS OR CONTENT AVAILABLE THROUGH THE SITE WILL CREATE ANY WARRANTY REGARDING ANY OF THE SINAPTICA ENTITIES OR THE SITE THAT IS NOT EXPRESSLY STATED IN THESE TERMS. WE ARE NOT RESPONSIBLE FOR ANY DAMAGE THAT MAY RESULT FROM THE SITE OR YOUR USE OF THE SITE. YOU UNDERSTAND AND AGREE THAT YOU USE ANY PORTION OF THE SITE AT YOUR OWN DISCRETION AND RISK, AND THAT WE ARE NOT RESPONSIBLE FOR ANY DAMAGE TO YOUR PROPERTY (INCLUDING YOUR COMPUTER SYSTEM OR MOBILE DEVICE USED IN CONNECTION WITH THE SITE) OR ANY LOSS OF DATA.

11.3 THE LIMITATIONS, EXCLUSIONS AND DISCLAIMERS IN THIS SECTION APPLY TO THE FULLEST EXTENT PERMITTED BY LAW. Sinaptica does not disclaim any warranty or other right that Sinaptica is prohibited from disclaiming under applicable law.

12. Limitation of Liability

12.1 TO THE FULLEST EXTENT PERMITTED BY LAW, IN NO EVENT WILL THE SINAPTICA ENTITIES BE LIABLE TO YOU FOR ANY INDIRECT, INCIDENTAL, SPECIAL, CONSEQUENTIAL OR PUNITIVE DAMAGES (INCLUDING DAMAGES FOR LOSS OF PROFITS, GOODWILL, OR ANY OTHER INTANGIBLE LOSS) ARISING OUT OF OR RELATING TO YOUR ACCESS TO OR USE OF, OR YOUR INABILITY TO ACCESS OR USE, THE SITE OR ANY MATERIALS OR CONTENT ON THE SITE, WHETHER BASED ON WARRANTY, CONTRACT, TORT (INCLUDING NEGLIGENCE), STATUTE, OR ANY OTHER LEGAL THEORY, AND WHETHER OR NOT ANY SINAPTICA ENTITY HAS BEEN INFORMED OF THE POSSIBILITY OF DAMAGE.

12.2 TO THE FULLEST EXTENT PERMITTED BY LAW, THE AGGREGATE LIABILITY OF THE SINAPTICA ENTITIES TO YOU FOR ALL CLAIMS ARISING OUT OF OR RELATING TO THE USE OF OR ANY INABILITY TO USE ANY PORTION OF THE SITE OR OTHERWISE UNDER THESE TERMS, WHETHER IN CONTRACT, TORT, OR OTHERWISE, IS LIMITED TO $100.

12.3 EACH PROVISION OF THESE TERMS THAT PROVIDES FOR A LIMITATION OF LIABILITY, DISCLAIMER OF WARRANTIES, OR EXCLUSION OF DAMAGES IS INTENDED TO AND DOES ALLOCATE THE RISKS BETWEEN THE PARTIES UNDER THESE TERMS. THIS ALLOCATION IS AN ESSENTIAL ELEMENT OF THE BASIS OF THE BARGAIN BETWEEN THE PARTIES. EACH OF THESE PROVISIONS IS SEVERABLE AND INDEPENDENT OF ALL OTHER PROVISIONS OF THESE TERMS. THE LIMITATIONS IN THIS SECTION 13 WILL APPLY EVEN IF ANY LIMITED REMEDY FAILS OF ITS ESSENTIAL PURPOSE.

13. Miscellaneous

13.1 General Terms. These Terms, together with the Privacy Policy available at [LINK] (the “Privacy Policy”), the Copyright Policy and any Additional Terms (defined below), are the entire and exclusive understanding and agreement between you and Sinaptica regarding your use of the Site. You may not assign or transfer these Terms or your rights under these Terms, in whole or in part, by operation of law or otherwise, without our prior written consent. We may assign these Terms at any time without notice or consent. The failure to require performance of any provision will not affect our right to require performance at any other time after that, nor will a waiver by us of any breach or default of these Terms, or any provision of these Terms, be a waiver of any subsequent breach or default or a waiver of the provision itself. Use of section headers in these Terms is for convenience only and will not have any impact on the interpretation of any provision. Throughout these Terms the use of the word “including” means “including but not limited to”. If any part of these Terms is held to be invalid or unenforceable, the unenforceable part will be given effect to the greatest extent possible, and the remaining parts will remain in full force and effect.

13.2 Governing Law. These Terms are governed by the laws of the State of California without regard to conflict of law principles that would result in the application of the laws of another jurisdiction. You and Sinaptica submit to the personal and exclusive jurisdiction of the state courts and federal courts located within County of San Francisco, California for resolution of any lawsuit or court proceeding permitted under these Terms. 

13.3 Privacy Policy. Please read the Privacy Policy HERE carefully for information relating to our collection, use, storage, disclosure of your personal information. The Privacy Policy is incorporated by this reference into, and made a part of, these Terms.

13.4 Additional Terms. Your use of the Site is subject to all additional terms, policies, rules, or guidelines applicable to the Site or certain features of the Site that we may post on or link to from the Site or that you agree to in connection with certain technology or services made available to you by or on behalf of Sinaptica (the “Additional Terms”). All Additional Terms are incorporated by this reference into, and made a part of, these Terms.

13.5 Consent to Electronic Communications. By using the Site, you consent to receiving certain electronic communications from us. You agree that any notices, agreements, disclosures, or other communications that we send to you electronically will satisfy any legal communication requirements, including that those communications be in writing. 

13.6 Contact Information. The Site is offered by Sinaptica, Inc., located at 245 First Street, 18th Floor, Cambridge, MA 02142. You may contact us by sending correspondence to that address or by emailing us at [email protected] .

13.7 Notice to California Residents. If you are a California resident, under California Civil Code Section 1789.3, you may contact the Complaint Assistance Unit of the Division of Consumer Services of the California Department of Consumer Affairs in writing at 1625 N. Market Blvd., Suite S-202, Sacramento, California 95834, or by telephone at (800) 952-5210 in order to resolve a complaint regarding the Site or to receive further information regarding use of the Site.

13.8 No Support. We are under no obligation to provide support for the Site. In instances where we may offer support, the support will be subject to published policies.

13.9 International Use. The Site is intended for visitors located within the United States. We make no representation that the Site is appropriate or available for use outside of the United States. Access to the Site from countries or territories or by individuals where such access is illegal is prohibited.

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Giovanni Frisoni

Scientific Advisor

Clinical neurologist, Full Professor of Clinical Neuroscience at the University of Geneva, Switzerland, and Director of the Memory Clinic of the Geneva University Hospital. Former Scientific Director at the National Alzheimer’s Centre in Brescia, Italy. Author of over 600 scientific papers listed in PubMed, imaging editor for Neurobiology of Aging, and founding editorial board member of The Lancet Neurology.

Has led national and international projects funded by the European Commission, IMI, the Alzheimer’s Association, Italian and Swiss Ministry of Health, and industry. Over the years, he has attracted about 50M euros in research funds. Chairman of Alzheimer’s Imaging Consortium at International Conference on Alzheimer’s Disease in 2010 and 2011. Honorary member of the Austrian Neurological Society and of the French Society of Neurology, he has received the Investigator Award Winner of European Academy of Neurology in 2016.

Simone Rossi MD, PhD

Scientific Advisor

Simone Rossi, MD, PhD, is a Professor of Human Physiology. He is also a Neurologist and Neurophysiologist, currently leading the Brain Investigation & Neuromodulation Lab (Si-BIN Lab) at the Department of Medicine, Surgery and Neuroscience, Neurology and Clinical Neurophysiology Unit, University of Siena, where he also leads the Parkinson’s disease clinical activity.

Dr. Rossi has a national full professorship habilitation in Neurology. He is the author of the popular scientific book “Il Cervello Elettrico” [The Electric Brain], Raffaello Cortina Ed., September 2020.

Dr. Rossi is an international leader in the field of noninvasive brain stimulation, where his contributions include: technical developments (one patent for a new sham coil for TMS); use and developments of noninvasive brain stimulation techniques (TMS, tDCS, tACS) as neuroimaging procedures in cognitive neuroscience, with a focus on memory, therapeutic neuromodulatory tools in neuropsychiatry, and neuroehnancement (including ethical issues); individuation of neurophysiological markers of psychiatric diseases; noninvasive investigation of neural plasticity mechanisms and brain connectivity, studied with EEG, TMS-EEG combination and rsFMRI. He also helps in the development of wearable robotic devices (in collaboration with Prof. Domenico Prattichizzo) to improve human health, for stroke people, Parkinson’s disease patients and tinnitus sufferers (three patents).

Dr. Rossi has authored 183 full text publications on peer-reviewed scientific journals indexed by Current Contents-Life Science (and 11 chapters in books), with an overall Impact Factor of about 804 (mean per publication: 4.2), H-index: 58. He has more than 17900 citations (see: http://scholar.google.it/ciations?user=2egMvssAAAAJ&hl=it, public GoogleScholar profile).

Dr. Rossi received his M.D. in 1987 at the University of Firenze, his specialization in Neurophysiopathlogy in 1990 at the University of Genova, and a second specialization in Neurology in 1999 at the University of Siena; in 1996, he obtained the PhD in “Pathophysiology of Nervous Functions”. He has been trained in neurology and neurophysiology in Siena, in Roma, under the supervision of Prof. Paolo Rossini and in Germany (Ulm, Freiburg).

He is or has been a member of the Editorial Boards of Behavioural Neurology, Brain Stimulation, ISNR Neurology, and Clinical Neurophysiology and is past President of the Italian Society of Psychophysiology & Cognitive Neuroscience. Currently, he is secretary of the Italian Society of Clinical Neurophysiology. He is also an occasional reviewer of 98 international scientific journals in neurology, neurophysiology, psychiatry and neuroscience areas (including Nature Reviews Neurology, Lancet Neurology, Neurology, Annals of Neurology, Journal of Neuroscience, Trends in Cognitive Sciences, Current Biology, Biological Psychiatry, American Journal of Psychiatry, Elife, etc.).

Dr. Rossi is Referee for the European Research Council, for the Medical Research Council (MRC) UK, for The French National Research Agency (ANR), for the Netherlands Organisation for Scientific Research, for the Israeli Scientific Foundation, for the Weston Brain Institute. He is a reviewer of the Italian Ministry of Research for the evaluation of scientific production of Italian Universities.

Dr. Rossi is or has been granted as Unit Leader in many Italian research projects and is responsible for the local neuroscientifc aspects in two European granted projects in Robotics.
Dr. Rossi is a Consultant for EBNeuro and for Neurocare Group Italy.

Lorenzo Di Gioacchino

Board Member

At F2i since 2008, he is a Partner and Head of the Legal Area. He provides assistance in the investment and divestment of the equity investments held by the Funds managed by F2i, in the legal aspects of the new Funds’ fund-raising activity, and provides general support to the company’s various departments.

Prior to joining F2i, he worked for four years at the Grande Stevens law firm, where he dealt with corporate, commercial and financial market law matters, with a focus on mergers and acquisitions. Previously he worked at the law firm Pavia and Ansaldo, also in the field of commercial and corporate law and he has been visiting lawyer at the London offices of law firm Weil, Gotshal & Manges and at London-based law firm Herbert Smith.

He serves on the Board of Directors of EI Towers and Sagat.

He graduated in Law from La Sapienza University, Rome.

Dinesh Moorjani

Board Observer

Dinesh Moorjani is a serial tech founder & CEO, venture capital investor, and adjunct professor. Dinesh was the Founder and CEO of Hatch Labs Inc., where he cofounded numerous software companies from ground up, including Tinder (NASDAQ: MTCH). Dinesh started several other software businesses, including Saffronart – a global eCommerce marketplace for Indian fine art and collectibles, backed by Sequoia Capital. He cofounded Kleverbeast, a no-code SaaS application development platform, and Monet Analytics, an AI SaaS business that decodes human emotion.

Dinesh served in numerous executive leadership roles at multinational corporations, including as Managing Director at Comcast Ventures, Sr. Vice President and Group Head of Mobility at IAC/InterActive Corp, and in various leadership roles at Samsung Electronics in the US and Asia. He built his early career in the Global Energy Practice at AD Little, Goldman Sachs, and as an early employee at Mainspring (IPO 2000, acquired by IBM 2001). Dinesh served as an independent board director at Alight (NYSE: ALIT) and on the advisory boards of Fortune 500 companies including American Express, Assurant, and Cox Automotive. He held the board observer seat at Zoox (acquired by Amazon), a leader in autonomous vehicles. Dinesh served as an advisor to Warburg Pincus, the global private equity firm, where he was previously an EIR sitting on company boards and co-investing alongside the firm.

Dinesh is a faculty advisor and senior lecturer at the UCLA Anderson School of Management, and guest lectures at Harvard, Stanford, and MIT. He serves on the Harvard Business School California Research Center Advisory Board. Dinesh supports disenfranchised youth and education through his non-profit work as a board director at the United Friends of the Children and the Organization for Social Media Safety. He also serves as a board trustee at the University of California, Merced. Dinesh earned his B.S. in Chemical Engineering from Northwestern University and MBA from Harvard. He is currently a Stanford University engineering doctoral student focused on climate innovation and sustainable finance.

Caitlin

Scientific Advisor

Dr. Ana Pereira completed her neurology residency at Harvard University, with sub-specialty trainings in Cognitive Neurology at Columbia University, Post-Doctoral Research Fellowship at Columbia University and Translational and Clinical Investigation at Rockefeller University in New York City where she was an Assistant Professor of Clinical Investigation before moving to Mount Sinai. Clinically, Dr. Pereira evaluates patients at the Barbara and Maurice Deane Center for Wellness and Cognitive Health at The Mount Sinai Hospital, having expertise in diagnosing and treating neurodegenerative disorders and other cognitive syndromes.     Dr. Pereira’s research focuses on furthering knowledge of the neurobiology of aging and Alzheimer’s disease, taking into account the selective vulnerability of glutamatergic neural circuits to synaptic changes in aging and neuronal loss in Alzheimer’s disease. She seeks to explore mechanisms underlying these susceptibilities along with effective therapeutic interventions. 

Ana Pereira MD

Scientific Advisor

Dr. Ana Pereira completed her neurology residency at Harvard University, with sub-specialty trainings in Cognitive Neurology at Columbia University, Post-Doctoral Research Fellowship at Columbia University and Translational and Clinical Investigation at Rockefeller University in New York City where she was an Assistant Professor of Clinical Investigation before moving to Mount Sinai. Clinically, Dr. Pereira evaluates patients at the Barbara and Maurice Deane Center for Wellness and Cognitive Health at The Mount Sinai Hospital, having expertise in diagnosing and treating neurodegenerative disorders and other cognitive syndromes.     Dr. Pereira’s research focuses on furthering knowledge of the neurobiology of aging and Alzheimer’s disease, taking into account the selective vulnerability of glutamatergic neural circuits to synaptic changes in aging and neuronal loss in Alzheimer’s disease. She seeks to explore mechanisms underlying these susceptibilities along with effective therapeutic interventions. 

Lisa Fosdick

Acting VP of Clinical

Lisa brings a decade of experience in neuromodulation for Alzheimer’s Disease (AD) guiding Functional Neuromodulation (deep brain stimulation of the fornix for AD) through two FDA trials and obtaining CE mark.  Prior to that her medical device experience spanned 7 years as Director of Data Management with NAMSA and Director of Clinical and Biostatistics at CVRx.  Earlier work included driving the creation of an HIV trials network spanning 23 countries with 4 regional coordinating centers to conduct several pharma-driven trials. Lisa has a Masters of Science in Biostatistics from the University of Minnesota. 

Casey Lynch

Strategic Advisor

Casey Lynch has more than 25 years of experience as an entrepreneur, executive and director with a focus on development of treatments for neurological disorders.  She is currently the CEO of Lighthouse Pharmaceuticals and Managing Partner of Sonoma Bioventures, an investment and advisory firm.  She has been a member of the board of directors of Longboard Pharmaceuticals (LBPH), a public company developing the next wave of neuropharmaceuticals, since February 2021 and a member of the review board of the Alzheimer’s Drug Development Foundation since September 2022. She previously co-founded and served as President and Chief Executive Officer and member of the board of directors of Cortexyme, Inc., a public biotechnology company, from July 2014 through January 2022, and as Chairman of Cortexyme’s Board of Directors from November 2018 through January 2022. She was a member of the board of directors of the California Life Science Association, a trade association representing California’s life science industry, from 2019 to 2021. Prior to co-founding Cortexyme, Ms. Lynch co-founded various companies and organizations in the biotechnology industry including Aspira Biosystems, an artificial antibody platform and NeuroInsights, an information, event and advisory firm focused on the intersection of neuropharma, neurodevices and neurodiagnostics.   Ms. Lynch holds a B.S. in Neuroscience from the University of California, Los Angeles, and an M.S. in Neuroscience from the University of California, San Francisco.

Anthony Arnold

Strategic Advisor

Anthony Arnold is the President & CEO of Sensydia Corporation; a leader in the field of artificial intelligence based, non-invasive cardiac assessment. Anthony is also CEO & Founder of the boutique medtech consulting firm, Precys.

Before being named CEO for Sensydia, Anthony spent eight years leading SetPoint Medical; a pioneer in the field of bioelectronic medicine dedicated to treating patients with debilitating inflammatory diseases. Arnold led the company and built a world-class team that delivered a revolutionary micro-implantable platform, novel therapeutic pathway and successful human trials in Europe and the US.

Anthony brings more than 20 years of experience in the development and commercialization of high-technology medical devices. Prior to SetPoint, Anthony served as Vice President of Marketing for Boston Scientific. Anthony was also Director of Marketing at Medtronic, responsible for the launch and explosive growth of the StealthStation navigation system. Prior to Medtronic, Anthony held a variety of positions of increasing responsibility in marketing and R&D with Smith+Nephew.

Jeffrey Cummings, MD ScD

Advisor

Jeffrey L. Cummings, MD, ScD, joined the UNLV School of Integrated Health Sciences in 2019 as research professor within the department of brain health. Dr. Cummings is the Joy Chambers-Grundy Professor of Brain Science, an endowed professorship. He is the Director of the Chambers-Grundy Center for Transformative Neuroscience, a center devoted to using the tools of neuroscience and neurologic drug development to transform people’s lives.

Prior to UNLV, Dr. Cummings served as founding director of the Cleveland Clinic Lou Ruvo Center for Brain Health in Las Vegas, and as director of the Mary S. Easton Center for Alzheimer’s Disease Research, and director of the Deane F. Johnson Center for Neurotherapeutics, both at UCLA.

A world-renowned Alzheimer’s researcher and leader of clinical trials, Dr. Cummings has been recognized for his scientific and leadership contributions with the American Geriatrics Society’s Henderson Award (2006), the national Alzheimer’s Association’s Ronald and Nancy Reagan Research Award (2008), and the American Association of Geriatric Psychiatry’s Distinguished Scientist Award (2010).

Dr. Cummings’ interests embrace clinical trials, developing new therapies for brain diseases, and the interface of neuroscience and society. Dr. Cummings has published nearly 800 articles and 44 books devoted to neuroscience, Alzheimer’s disease, and clinical trials.

Dr. Cummings received the Society for Behavioral and Cognitive Neurology’s Lifetime Achievement Award (2017), the International Society of CNS Drug Development’s Leadership and Achievement Award and the national Alzheimer’s Association’s Bengt Winblad Lifetime Achievement Award (2018).

Additionally, he was featured in Gentleman’s Quarterly (June 2009) as a “Rock Star of Science. ™” In addition to his work at UNLV, Dr. Cummings is professor of medicine (Neurology) at Cleveland Clinic Lerner College of Medicine at Case Western Reserve University, and he is principal investigator/director of the National Institute of General Medical Sciences-funded Center for Neurodegeneration and Translational Neuroscience.

Henry Peck

Digital Biomarker Advisor

Henry the Vice President of Growth & Strategy at LSI (Life Science Intelligence™), an ecosystem of software, services, and events that enables thousands of medtech leaders around the world access the intelligence and relationships needed to build breakthrough businesses. Henry’s role spans both the company’s global partnering events, who’s emerging company alumni raised over $1.45 Billion in capital in 2022, and its Medtech Market Intelligence business, which is a trusted partner for syndicated and custom research and data solutions to the largest Medtech, Life Science, and Professional Services organizations, from Medtronic to McKinsey & Co.

Prior to his current role, Henry was the Director of Strategy and Marketing at Altoida, a precision neurology company pioneering novel digital cognitive assessment and diagnostics with augmented reality and machine learning. As one of the first team members beyond the founding scientific team, Henry was integral in winning FDA Breakthrough Device Designation for the technology’s prognostic and diagnostic application in Alzheimer’s disease, establishing partnerships and multi-million dollar commercial deals with global pharmaceutical companies and digital therapeutics providers, and securing bridge financing from new and existing investors including Whitecap Venture Partners, M Ventures (Merck KGaA), Hikma Ventures, HonorHealth, and more.

Henry began his career in robotics, primarily with Auris Health (Johnson & Johnson) where he supported upstream strategic marketing and portfolio management for a novel suite of robotically-driven stapling and advanced energy devices leveraging Ethicon’s portfolio of laparoscopic surgical devices (ECHELON™, ENSEAL™, HARMONIC). An engineer by trade, Henry holds a BS in Mechanical Engineering from Carnegie Mellon University and has conducted research in upper-limb extremity prosthesis and human performance augmentation via CMU’s Human-Computer Interaction Institute and Robotics Institute.

Alessio Travaglia

Scientific Advisor

Neuroscientist with over 15 years of experience in basic and translational neuroscience, in academia, non-profit, management consulting, and venture philanthropy.

Currently I work as the Director, Neuroscience at the Foundation for the National Institutes of Health (FNIH). In this role, I lead the Neuroscience programs, facilitate the advancement and execution of innovative Public-Private Partnerships, engage international participation from government, industry, academia, patient-advocacy and private sector organizations.

Jim Schwoebel

SW/ML Advisor

Jim is an Engineering Manager @ Verily building out Verily Workbench (formerly Terra), a scalable, secure research platform to help biomedical researchers accelerate scientific discoveries. He has over 10 years of experience building startups and R&D partnerships in the areas of machine learning, digital health, and software engineering.

Prior to joining Verily, Jim was the CEO of NeuroLex Laboratories, a company focused on using voice as a marker for early diagnosis of psychiatric and neurological diseases. Before being acquired by Sonde Health, NeuroLex had key partnerships in biopharma, grew its data bank to over 500,000 voice files and expanded its core SurveyLex product to thousands of users. Jim received his BS in Biomedical Engineering from Georgia Tech.

Emiliano Santarnecchi PhD, PhD

Scientific Co-Founder

Emiliano Santarnecchi is an Associate Professor of Radiology at Harvard Medical School (HMS), and the director of the Precision Neuroscience & Neuromodulation program (PNN) and the Network Control Laboratory at the Gordon Center for Medical Imaging at Massachusetts General Hospital (MGH).

Dr. Santarnecchi’s program focuses on combining multimodal neuroimaging (e.g., MRI, fMRI, DTI, PET) and electrophysiology (e.g., EEG, EMG, MEG) methods for the identification of novel biomarkers and the development of therapeutic approaches for patients with neurological and psychiatric conditions.

In particular, Dr. Santarnecchi’s research is centered around the development of personalized, network-based Noninvasive Brain Stimulation (NiBS) approaches to modulate brain plasticity, guide connectome rewiring and enhance cognitive function, with the ultimate goal of promoting Brain Health and healthy Aging. His team is currently working on machine learning and AI-based solutions for perturbation-based brain connectivity analysis (TMS-EEG, fMRI), NIBS approaches to modulate sleep and memory, high-frequency transcranial electrical stimulation interventions for the treatment of Alzheimer’s disease and Frontotemporal dementia, and novel fMRI markers of disease progression in patients with brain tumors.

Giacomo Koch MD, PhD

Scientific Co-Founder

Giacomo Koch, MD. PHD is a neurologist and neuroscientist. He is Full Professor of Human Physiology at University of Ferrara and leads the non-invasive cortical stimulation lab at Santa Lucia Foundation in Rome, Italy.

Prof. Koch has a world-class experience in the field of clinical neurophysiology. His main expertise is in the application of non-invasive brain stimulation techniques such as transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), mainly used in combination with structural and functional magnetic resonance imaging (MRI) and with electroencephalography (EEG).

The main goals of his research are to understand the mechanisms underlying cortical plasticity and cortical connectivity in the healthy human brain, to develop novel therapeutic approaches to promote recovery of neurological functions trough methods of non-invasive brain stimulation. He pioneered novel research based on multifocal TMS to investigate in real-time the activation of cortical circuits and to study the mechanisms of cortico-cortical plasticity. Prof. Koch performed several clinical trials evaluating the therapeutic efficacy of rTMS in neurological disorders such as Parkinson’s disease and stroke.

The main current focus of his research is on the field of Alzheimer’s disease (AD) and dementia. Prof. Koch conducted a series of clinical studies that led to the first clinical evidence that therapy with dopaminergic agonists such as rotigotine, may slow cognitive decline and preserve functional activities in patients with AD.  The translational approach of his research has been directed in the past 10 years to find novel therapies for AD that are based on personalized non-invasive brain stimulation therapies.

He is the author of >320 peer-reviewed publications and several book chapters. H index: 65 (Scopus).

Greg Harper

Acting VP of R&D

Mr. Harper has a proven track record in program management and leading global teams across all phases of the product development lifecycle -    from ideation & feasibility, through design & development, production ramp-up, installed base maintenance, and end-of-life.   

He has held leadership roles in Neuronetics, Philips Medical Imaging, GE Appliances, GE Medical, and GE Aerospace. Mr. Harper has directed global teams in the US, France, Israel, India, and China with a focus on talent development, and creating a culture of innovation, functional excellence, and process controls.    Mr. Harper holds a BS in Electrical Engineering from Valparaiso University, and an MBA from the University of Wisconsin.

Chris Thatcher

Strategic Advisor

A Senior Life Sciences Executive experienced as a Board Member, CEO and Divisional President in the commercialization of Class I, II, and III medical devices, for public or privately owned companies, with capital equipment, disposables, implantable or service agreements utilized in the operating room or office based, domestically and internationally, in enterprises ranging from $20M to $425M in annual revenues, converting debt, venture funding or Initial Public Offering proceeds into successful turnarounds by accelerate revenue growth, margin expansion, operating leverage and ultimately EBITDA for their respective enterprises.

Ken Mariash

CEO

As CEO of Sinaptica, Ken is leading the team to advance the company’s personalized precision neuromodulation therapy for Alzheimer’s.

Prior to Sinaptica, Ken has 20+ years leading and growing new business ventures on both the ‘Buy Side’ and the ‘Build Side.’

He started his career in management consulting at Charles River Associates, then jumped to industry at CSL, then Baxter BioScience (now Takeda), and Boston Scientific, with leadership roles in marketing, strategy, and corporate development. At Boston Scientific’s nearly $1B Neuromodulation division, he was the global commercial lead for the highly successful Cosman RF ablation business he helped acquire.

He also built the division’s Strategy function, providing leadership in areas including strategic planning, BD assessment, R&D portfolio management, digital strategy, and investments in next-gen platforms & new indications. In 2019 he joined EBT Medical, a venture-backed, clinical-stage startup developing a disruptive neuromodulation device for overactive bladder, where he oversaw all commercial aspects.

Rich Macary

President

Rich Macary is the President of Sinaptica Therapeutics, a clinical-stage electromagnetic therapeutics company developing a novel, noninvasive closed loop neuromodulation approach for the treatment of Alzheimer’s disease.  As one of the company’s co-founders, Rich helped drive product development and partnering efforts as well as securing FDA Breakthrough Device Designation for the company’s proprietary SinaptiStimTM- AD System.  Prior to his current role, Rich was a consultant, strategic advisor and a senior executive at Sarepta Therapeutics, a global biotechnology company and leader in RNA based therapeutics and genetic medicines targeting rare diseases. In his role as Vice President of Business Development, Rich focused on developing new opportunities and therapeutic targets for the company’s RNA technologies as well as complimentary technologies and related IP.  Prior to and post his roles at Sarepta, Rich held several senior executive roles at Delos, a wellness real estate and technology company, where he lead business development, strategic investments and overall strategy as both President of Delos Ventures and Chief Strategy Officer.  In his roles at Delos, Rich achieved a number of key accomplishments including conceiving, developing and launching the Well Living Lab, a Delos and Mayo Clinic collaboration to study the impact of indoor environments on the health and well-being of building occupants. Rich spent the prior 15  years as a corporate consultant, advisor and analyst to both institutional and high-net-worth investors as well as a consultant, advisor, investor and board member to several public and private early to mid-stage companies operating in a diverse range of industries including biotechnology, medical devices, software, fintech and consumer products among others. Rich currently holds several board positions and remains a managing partner of Macary Advisors, a biotech/medtech consulting and advisory firm currently engaged with several promising companies within the fields of diagnostics, therapeutics, medical devices and digital health.  His research and opinions have appeared in many media outlets including Forbes, The Wall Street Journal, Wired, CNN, Barron’s, Reuters and Bloomberg.